|
KMID : 0380620100420060755
|
|
Korean Journal of Food Science and Technology
2010 Volume.42 No. 6 p.755 ~ p.761
|
|
|
Anti-cancer and Anti-inflammatory Effects of Mung Bean and Soybean Extracts
|
|
Imm Jee-Young
Kim Seok-Joong
|
|
|
Abstract
|
|
|
|
The quinone reductase (QR) inducing activities of mung bean and soybean solvent extracts were compared using murine hepatoma cells (Hepa 1c1c7). The mung bean extracts (ethylacetate and ethanol) showed higher chemoprevention index values (7.88-8.22) than those of soybean extracts (2.9-5.2) from four different cultivars. The mung bean extracts also had significantly higher inhibitory effects (47-62% at 100 μg/mL) than the soybean extracts (15-42% at 100 μg/mL) against the production of nitric oxide and prostaglandin E2 in lipopolysccharide stimulated macrophage RAW264.7 cells without cytotoxicity. Among seven recovered fractions of mung bean ethanol extract obtained by C 18 silica flash column chromatography, the most non-polar fraction exhibited the highest chemoprevention index of 10.4.
|
|
|
KEYWORD
|
|
|
mung bean extract, quinone reductase, nitric oxide, prostaglandin E2, cytotoxicity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|